SUMO Regulation of Cellular Processes
ISBN-13:
9789400791442
ISBN-10:
9400791445
Edition:
2009
Author:
Victor Willson
Publication date:
2014
Publisher:
Springer
Format:
Paperback
339 pages
FREE US shipping
Book details
ISBN-13:
9789400791442
ISBN-10:
9400791445
Edition:
2009
Author:
Victor Willson
Publication date:
2014
Publisher:
Springer
Format:
Paperback
339 pages
Summary
SUMO Regulation of Cellular Processes (ISBN-13: 9789400791442 and ISBN-10: 9400791445), written by authors
Victor Willson, was published by Springer in 2014.
With an overall rating of 4.3 stars, it's a notable title among other
books. You can easily purchase or rent SUMO Regulation of Cellular Processes (Paperback) from BooksRun,
along with many other new and used
books
and textbooks.
And, if you're looking to sell your copy, our current buyback offer is $0.41.
Description
Over a decade ago, a small cellular protein of 12 kDa, with 18% homology to the well-known ubiquitin protein, was co-discovered and termed Small Ubiquitin-like Modifier, or SUMO. Sumoylation is a post-translational modification that utilizes SUMO as the modifier group covalently attached to target substrates. This state-of-the art review on the sumoylation system deals with protein modification as it pertains to regulation of diverse cellular functions. Each chapter has been written by a leading researcher and covers the role of sumoylation in fundamental biochemical activities (transcription, RNA processing, chromatin remodelling, DNA repair, nucleocytoplasmic transport, ion channel regulation, and metabolic pathways). The text also examines the part sumoylation plays in critical cellular processes such as mitosis, meiosis, differentiation, senescence, and apoptosis. Lastly, the emerging role of sumoylation in specific diseases, including cancer and diabetes as well as neurodegenerative ones, is explored with an emphasis on defining molecular mechanisms that may provide new targets for treatment or prevention. While SUMO was discovered more than 10 years ago, this is still a relatively young field, and much remains to be discovered about the biochemical and biological properties of this modification system. In just the last few years, it has become clear that sumoylation modifies hundreds of cellular proteins, and there has been increased appreciation for the breadth of cellular functions that are impacted by this post-translational modification.
We would LOVE it if you could help us and other readers by reviewing the book
Book review
Congratulations! We have received your book review.
{user}
{createdAt}
by {truncated_author}