Functional Genetics and Psychiatric Disorders: An Exploration of Functional Genetic Variants in Candidate Genes for Psychiatric Disorders
ISBN-13:
9783844384161
ISBN-10:
3844384162
Author:
Robert Moyer, Wolfgang Sadee
Publication date:
2011
Publisher:
LAP LAMBERT Academic Publishing
Format:
Paperback
96 pages
FREE US shipping
Book details
ISBN-13:
9783844384161
ISBN-10:
3844384162
Author:
Robert Moyer, Wolfgang Sadee
Publication date:
2011
Publisher:
LAP LAMBERT Academic Publishing
Format:
Paperback
96 pages
Summary
Functional Genetics and Psychiatric Disorders: An Exploration of Functional Genetic Variants in Candidate Genes for Psychiatric Disorders (ISBN-13: 9783844384161 and ISBN-10: 3844384162), written by authors
Robert Moyer, Wolfgang Sadee, was published by LAP LAMBERT Academic Publishing in 2011.
With an overall rating of 4.3 stars, it's a notable title among other
books. You can easily purchase or rent Functional Genetics and Psychiatric Disorders: An Exploration of Functional Genetic Variants in Candidate Genes for Psychiatric Disorders (Paperback) from BooksRun,
along with many other new and used
books
and textbooks.
And, if you're looking to sell your copy, our current buyback offer is $0.55.
Description
Drug addiction is a chronic disorder characterized by compulsive drug seeking and taking despite serious negative consequences. Association studies have identified a number of candidate genes harboring variants associated with susceptibility to addiction, but the causative variants frequently remain unknown. A solution to the challenge of identifying causative variants is the thorough characterization of functional genetic polymorphisms and their effects on regulation of candidate genes. I focused on candidate genes for drug addiction (ARRB2, DRD2, and DRD3) and made some novel and significant findings: The effects of two intronic SNPs in the human dopamine receptor D2 (DRD2) gene, previously shown to alter DRD2 alternative splicing, were confirmed in human brain autopsy tissues obtained from a population of cocaine abusers and controls. The same SNPs were significantly associated with cocaine abuse. The results of this study contribute to our understanding of the functional genetic variation in important candidate genes and have the potential to improve the prevention and treatment of drug addiction and other psychiatric disorders.
We would LOVE it if you could help us and other readers by reviewing the book
Book review
Congratulations! We have received your book review.
{user}
{createdAt}
by {truncated_author}