Transgenic Models of Human Viral and Immunological Disease (Current Topics in Microbiology and Immunology, 206)
ISBN-13:
9783642852107
ISBN-10:
3642852106
Edition:
Softcover reprint of the original 1st ed. 1996
Author:
Francis V. Chisari, Michael B.A. Oldstone
Publication date:
2013
Publisher:
Springer
Format:
Paperback
359 pages
FREE US shipping
Book details
ISBN-13:
9783642852107
ISBN-10:
3642852106
Edition:
Softcover reprint of the original 1st ed. 1996
Author:
Francis V. Chisari, Michael B.A. Oldstone
Publication date:
2013
Publisher:
Springer
Format:
Paperback
359 pages
Summary
Transgenic Models of Human Viral and Immunological Disease (Current Topics in Microbiology and Immunology, 206) (ISBN-13: 9783642852107 and ISBN-10: 3642852106), written by authors
Francis V. Chisari, Michael B.A. Oldstone, was published by Springer in 2013.
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Description
Most diseases are multifactoral. Transgenic technology permits gene(s) of interest to be expressed in a small manipulatable laboratory animal model. By this process, murine models of human infections can be developed and studied; effects of cytokines in vivo, focally expressed in unique cells can be established and manipulated, and a variety of autoimmune disorders, mimicking human disease can be constructed. In this volume, these approaches for study of human immunodeficiency virus, hepatitis virus, viruses causing tumors and chronic degenerative disorders are described. Also included are chapters of transgenic models of autoimmune disorders like diabetes, systemic lupus and ankylosing spondylitis.
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