Invertebrate Cytokines and the Phylogeny of Immunity: Facts and Paradoxes (Progress in Molecular and Subcellular Biology, 34)
ISBN-13:
9783642622366
ISBN-10:
3642622364
Edition:
Softcover reprint of the original 1st ed. 2004
Author:
Werner E. G. Müller, Alain Beschin
Publication date:
2012
Publisher:
Springer
Format:
Paperback
195 pages
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Book details
ISBN-13:
9783642622366
ISBN-10:
3642622364
Edition:
Softcover reprint of the original 1st ed. 2004
Author:
Werner E. G. Müller, Alain Beschin
Publication date:
2012
Publisher:
Springer
Format:
Paperback
195 pages
Summary
Invertebrate Cytokines and the Phylogeny of Immunity: Facts and Paradoxes (Progress in Molecular and Subcellular Biology, 34) (ISBN-13: 9783642622366 and ISBN-10: 3642622364), written by authors
Werner E. G. Müller, Alain Beschin, was published by Springer in 2012.
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Description
Based on the assumption that invertebrates as well as vertebrates possess factors regulating hematopoiesis, response to infection or wounding, studies dealing with the evolution of immunity have focused on the isolation and characterization of putative cytokine-related molecules from invertebrates. Until recently, most of our knowledge of cytokine- and cytokine receptor-like molecules in invertebrates has relied on functional assays and similarities at the physicochemical level. As such, a phylogenetic relationship between invertebrate cytokine-like molecules and invertebrate counterparts could not be convincingly demonstrated. In the present book, recent studies demonstrating cytokine-like activities and related signaling pathways in invertebrates are critically reviewed, focusing on findings from molecular biology and taking advantage of the completion of the genome from the fly Drosophila and the worm Caenorhabditis elegans.
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