Restriction Endonucleases (Nucleic Acids and Molecular Biology, 14)
ISBN-13:
9783540205029
ISBN-10:
3540205020
Edition:
2004
Author:
Alfred Pingoud
Publication date:
2004
Publisher:
Springer
Format:
Hardcover
469 pages
Category:
Biochemistry
,
Chemistry
,
Molecular Biology
,
Evolution
,
Biotechnology
,
Biological Sciences
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Book details
ISBN-13:
9783540205029
ISBN-10:
3540205020
Edition:
2004
Author:
Alfred Pingoud
Publication date:
2004
Publisher:
Springer
Format:
Hardcover
469 pages
Category:
Biochemistry
,
Chemistry
,
Molecular Biology
,
Evolution
,
Biotechnology
,
Biological Sciences
Summary
Restriction Endonucleases (Nucleic Acids and Molecular Biology, 14) (ISBN-13: 9783540205029 and ISBN-10: 3540205020), written by authors
Alfred Pingoud, was published by Springer in 2004.
With an overall rating of 4.4 stars, it's a notable title among other
Biochemistry
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Biochemistry
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Description
Restriction enzymes are highly specific nucleases which occur ubiquitously among prokaryotic organisms, where they serve to protect bacterial cells against foreign DNA. Many different types of restriction enzymes are known, among them multi-subunit enzymes which depend on ATP or GTP hydrolysis for target site location. The best known representatives, the orthodox type II restriction endonucleases, are homodimers which recognize palindromic sequences, 4 to 8 base pairs in length, and cleave the DNA within or immediately adjacent to the recognition site. In addition to their important biological role (up to 10 % of the genomes of prokaryotic organisms code for restriction/modification systems!), they are among the most important enzymes used for the analysis and recombination of DNA. In addition, they are model systems for the study of protein-nucleic acids interactions and, because of their ubiquitous occurence, also for the understanding of the mechanisms of evolution.
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