The design and analysis of sequential clinical trials (Ellis Horwood series in mathematics and its applications)
ISBN-13:
9780853124047
ISBN-10:
0853124043
Author:
John Whitehead
Publication date:
1983
Publisher:
Halsted Press
Format:
Hardcover
272 pages
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Book details
ISBN-13:
9780853124047
ISBN-10:
0853124043
Author:
John Whitehead
Publication date:
1983
Publisher:
Halsted Press
Format:
Hardcover
272 pages
Summary
The design and analysis of sequential clinical trials (Ellis Horwood series in mathematics and its applications) (ISBN-13: 9780853124047 and ISBN-10: 0853124043), written by authors
John Whitehead, was published by Halsted Press in 1983.
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Description
This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include -spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.
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