Mechanisms of Protease Action
ISBN-13:
9780849369018
ISBN-10:
0849369010
Edition:
1
Author:
Laszlo Polgar
Publication date:
1989
Publisher:
CRC Press
Format:
Hardcover
232 pages
Category:
Biochemistry
,
Chemistry
,
Biology
,
Biological Sciences
FREE US shipping
Book details
ISBN-13:
9780849369018
ISBN-10:
0849369010
Edition:
1
Author:
Laszlo Polgar
Publication date:
1989
Publisher:
CRC Press
Format:
Hardcover
232 pages
Category:
Biochemistry
,
Chemistry
,
Biology
,
Biological Sciences
Summary
Mechanisms of Protease Action (ISBN-13: 9780849369018 and ISBN-10: 0849369010), written by authors
Laszlo Polgar, was published by CRC Press in 1989.
With an overall rating of 3.5 stars, it's a notable title among other
Biochemistry
(Chemistry, Biology, Biological Sciences) books. You can easily purchase or rent Mechanisms of Protease Action (Hardcover) from BooksRun,
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Biochemistry
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Description
A uniform treatment of the four protease groups and a discussion of the differences and similarities in their action is presented in this important new publication. Serine, cysteine, aspartate, and zinc proteases are systematically discussed by nomenclature, evolution, specificity and their regulatory role. The chemistry of the peptide bond, including the catalysis of ester and peptide hydrolyses, is explained.For each protease group the emphasis is placed on the structure and function. Kinetics, enzyme modifications, isotope effects, subzero temperature investigations, nuclear magnetic resonance measurements, X-ray diffraction data, binding of transition-state analogs, zymogen activation, and site-specific mutagenesis are combined to rationalize the action of proteases. Both natural and synthetic inhibitors are considered because of their importance in mechanistic studies and drug design.
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