9783319188805-3319188801-The Male Role in Pregnancy Loss and Embryo Implantation Failure (Advances in Experimental Medicine and Biology, 868)

The Male Role in Pregnancy Loss and Embryo Implantation Failure (Advances in Experimental Medicine and Biology, 868)

ISBN-13: 9783319188805
ISBN-10: 3319188801
Edition: 1st ed. 2015
Publication date: 2015
Publisher: Springer
Format: Hardcover 238 pages
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Book details

ISBN-13: 9783319188805
ISBN-10: 3319188801
Edition: 1st ed. 2015
Publication date: 2015
Publisher: Springer
Format: Hardcover 238 pages

Summary

Acknowledged author wrote The Male Role in Pregnancy Loss and Embryo Implantation Failure (Advances in Experimental Medicine and Biology, 868) comprising 238 pages back in 2015. Textbook and eTextbook are published under ISBN 3319188801 and 9783319188805. Since then The Male Role in Pregnancy Loss and Embryo Implantation Failure (Advances in Experimental Medicine and Biology, 868) textbook was available to sell back to BooksRun online for the top buyback price or rent at the marketplace.

Description

Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions might also be related to the transmission of previously unrecognized chromosomal micro-deletions and duplications, or via the epigenetic dysregulation of early embryonic gene function by spermatozoal microRNAs or alterations in sperm DNA methylation patterning, or by DNA damage secondary to either reactive oxygen species or environmental toxicants. In addition, the composition of seminal plasma has been found to be highly complex, containing many factors that play important roles in altering the uterine environment and the female immune system permissive of embryo implantation and trophectoderm outgrowth leading to successful pregnancy. Coverage includes an examination of both spermatozoa and seminal fluid component factors.

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