9781466551404-1466551402-Handbook of Ion Channels

Handbook of Ion Channels

ISBN-13: 9781466551404
ISBN-10: 1466551402
Edition: 1
Publication date: 2015
Publisher: CRC Press
Format: Hardcover 691 pages
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Book details

ISBN-13: 9781466551404
ISBN-10: 1466551402
Edition: 1
Publication date: 2015
Publisher: CRC Press
Format: Hardcover 691 pages

Summary

Acknowledged author wrote Handbook of Ion Channels comprising 691 pages back in 2015. Textbook and eTextbook are published under ISBN 1466551402 and 9781466551404. Since then Handbook of Ion Channels textbook was available to sell back to BooksRun online for the top buyback price or rent at the marketplace.

Description

The New Benchmark for Understanding the Latest Developments of Ion Channels

Ion channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of cells. In nonexcitable tissues, they also help regulate basic salt balance critical for homeostasis. All of these features make ion channels important targets for pharmaceuticals.

Handbook of Ion Channels illustrates the fundamental importance of these membrane proteins to human health and disease. Renowned researchers from around the world introduce the technical aspects of ion channel research, provide a modern guide to the properties of major ion channels, and present powerful methods for modeling ion channel diseases and performing clinical trials for ion channel drugs.

Conveniently divided into five parts, the handbook first describes the basic concepts of permeation and gating mechanisms, balancing classic theories and the latest developments. The second part covers the principles and practical issues of both traditional and new ion channel techniques and their applications to channel research. The third part organizes the material to follow the superfamilies of ion channels. This part focuses on the classification, properties, gating mechanisms, function, and pharmacology of established and novel channel types. The fourth part addresses ion channel regulation as well as trafficking and distribution. The final part examines several ion channel-related diseases, discussing genetics, mechanisms, and pharmaceutical advances.

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